Procaine penicillin G and Dihydrostreptomycin sulphate injection(20:20)
Composition:
Contains per ml:
Procaine penicillin G 200 000 IU
Dihydrostreptomycin sulphate 200 mg
Solvents ad. 1ml
Description:
The combination of procaine penicillin G and dihydrostreptomycin acts additive and in some cases synergistic. Procaine penicillin G is a small-spectrum penicillin with a bactericidal action against mainly Gram-positive bacteria like Campylobacter, Clostridium, Corynebacterium, Erysipelothrix, Haemophilus, Listeria, Pasteurella, penicillinase negative Staphylococcus and Streptococcus spp. Dihydrostreptomycin is an aminoglycoside with a bactericidal action against mainly Gram-negative bacteria like E. coli, Klebsiella, Pasteurella, Salmonella and Staphylococcus spp.
Indications:
Arthritis, mastitis and gastrointestinal, respiratory and urinary tract infections caused by penicillin and dihydrostreptomycin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Klebsiella, Listeria, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp., in calves, cattle, goats, sheep and swine.
Dosage and Administration:
For intramuscular administration,
Cattle : 1 ml. per 20 kg. body weight for 3 days.
Calves, goats, sheep and swine : 1 ml. per 10 kg. body weight for 3 days.
The maximum dose volume administered at one site should not exceed 15 ml for horses, 6ml for cattle, 3ml for sheep and 1.5ml for pigs.
Contraindications:
-Hypersensitivity to penicillin, procaine and/or aminoglycosides.
-Administration to animals with a serious impaired renal function.
-Concurrent administration with tetracyclines, chloramphenicol, macrolides and lincosamides.
Side Effects:
- Administration of therapeutic dosages of procaine penicillin G can result in abortion in sows.
- Ototoxity, neurotoxicity or nephrotoxicity.
- Hypersensitivity reactions.
Precaution:
Should not be use for animal which allergy to penicillin. Shake well before use.
Withdrawal time:
- For kidney : 45 days.
- For meat : 21 days.
- For milk : 3 days.
Keep out of the touch of children, and store in the cool place.